(1):
(n.) A mistress of a family, who is a lady; a woman in authority; especially, a lady.
(2):
(n.) A mother; - applied to human beings and quadrupeds.
(3):
(n.) A woman in general, esp. an elderly woman.
(4):
(n.) The mistress of a family in common life, or the mistress of a common school; as, a dame's school.