Hierapolis (hî'e-răp'o-lĭs), sacred city. A city in Proconsular Asia, Colossians 4:13, near the river Lycus, and in sight of Laodicea, which was about 5 miles to the south. It stood on a high bluff, with a high mountain behind it. In the city was the famous temple of Pluto, remains of which are still to be seen. The ruins of the city are extensive, as temples, churches, a triumphal arch, a theatre, gymnasium, baths, and highly ornamented sarcophagi.