Lys'ias. (dissolving). A nobleman of the blood-royal, 1 Maccabees 3:32; 2 Maccabees 11:1, who was entrusted by Antiochus Epiphanes, (cir. B.C. 166), with the government of southern Syria and the guardianship of his son, Antiochus Eupator. 1 Maccabees 3:32; 2 Maccabees 10:11.
After the death of Antiochus Epiphanes, B.C. 184, Lysias assumed the government as guardian of his son, who was yet a child. 1 Maccabees 6:17. In B.C. 164, he, together with his ward, fell into the hands of Demetrius Soter, who put them both to death. 1 Maccabees 7:2-4; 2 Maccabees 14:2.