(1):
(superl.) Hence, hobbling; limping; inefficient; imperfect.
(2):
(superl.) To some degree disabled by reason of the imperfect action of a limb; crippled; as, a lame man.
(3):
(v. t.) To make lame.
(4):
(superl.) Moving with pain or difficulty on account of injury, defect, or temporary obstruction of a function; as, a lame leg, arm, or muscle.