(Hebrews E'tsem, עֶצֶם, a bone, in pause A'tsem, עָצֶם; Sept. Ἀσέμ v. r. Ἀσόμ, Ι᾿ασόν ), a city in the tribe of Simeon, originally included within the southern territory of Judah, in the neighborhood of Balah (or Bilhah) and Eltolad (or Tolad) (Joshua 15:29; Joshua 19:3; 1 Chronicles 4:29, in which last passage it is Anglicized "Ezem," Sept. Βοασόμ v. r. Αἰσέμ ). These notices afford only a slight ground for a conjectural location, perhaps in the great plain at the south-west extremity of the tribe, possibly at the ruins on Tell Akhmar (Van de Velde, Map).
Of this place Dr. Tristram thinks (Bible Places, p. 23) a trace remains in the name of the Azazimeh Arabs who occupy the region in question. (See IIM).