The first high priest of the family of Boethus in the Temple of Jerusalem. He was a native of Alexandria. He owed his appointment as high priest to his daughter Mariamne, who captivated Herod by her beauty, the king advancing her father in office in order to give Mariamne a certain rank when he made her his wife. When Herod subsequently put away this second Mariamne, Simeon was deposed from the high-priest-hood.