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Fausset's Bible Dictionary
(See Proverbs 25:20, "as vinegar upon nitre so is he that singeth songs to an heavy heart." To the feelings of the heavy at heart songs are as grating and irritative as acid poured on alkali. Nitre is carbonate of soda or potash; mixed with oil it was used as "soap" (borit ): Jeremiah 2:22..)
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Fausset, Andrew R. Entry for 'Nitre'. Fausset's Bible Dictionary. https://www.studylight.org/dictionaries/eng/fbd/n/nitre.html. 1949.