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Hastings' Dictionary of the Bible
CARCHEMISH was the northern capital of the Hittite empire, but was probably also of consequence before the era of the Hittites, as it commanded the principal ford of the Euphrates on the right bank, and was therefore indispensable to travel and commerce in Northern Syria. It was shown by George Smith to have lain on the site of the modern Jerablus or Hierapolis. It was an obstacle to the march of the invading Egyptians about b.c. 1600. Several Assyrian conquerors attempted to capture it. It was taken finally by Sargon in b.c. 717 (cf. Isaiah 10:9 ), after which it became the capital of an Assyrian province. Here Nebuchadrezzar defeated Pharaoh-necho in b.c. 605, and thus ended the latest native Egyptian rÃ§gime in Asia ( Jeremiah 46:2 , 2 Chronicles 35:20 ).
J. F. McCurdy.
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Hastings, James. Entry for 'Carchemish'. Hastings' Dictionary of the Bible. https://www.studylight.org/dictionaries/eng/hdb/c/carchemish.html. 1909.