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(a.) Of, pertaining to, or designating, a substance (called ophelic acid) extracted from a plant (Ophelia) of the Gentian family as a bitter yellowish sirup, used in India as a febrifuge and tonic.
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Webster, Noah. Entry for 'Ophelic'. Noah Webster's American Dictionary. https://www.studylight.org/dictionaries/eng/web/o/ophelic.html. 1828.