Personal greetings (16:1-27)
The person who took this letter to Rome was Phoebe, a woman well respected for her work in the church in Cenchreae, one of the seaports of Corinth. She had been a tireless helper of Paul and many others, and Paul asks the Roman Christians to welcome her (16:1-2).
Paul then sends greetings to a number of people whom he had met during his missionary travels and who now lived in Rome. First among these were Paul's loyal friends, Aquila and Priscilla. They were now back in Rome after a time in Ephesus, and a local church met in their home (3-5; cf. Acts 18:1-3; Acts 18:18-19; Acts 18:24-26). Little is known of most of the others whom Paul mentions. There were both Jews and Gentiles, and some, such as Junias and Andronicus, were prominent Christian workers (6-11). Paul mentions a number of women who were well known for their Christian service, and one in particular who had been a great personal help to him (12-13). He sends greetings to two additional households where groups of Christians met (14-16).
A warning is given to beware of those who, by their smooth talk, mislead people and create divisions within the fellowship (17-18). Wise leaders, however, will not be deceived by flattering speech. They will recognize Satan at work among them, and will triumph over him (19-20).
Various people who were with Paul in Corinth join him in sending greetings. These include his secretary Tertius and his host Gaius (21-24; cf. 1 Corinthians 1:14). Paul finishes his letter with a further note of praise to God, who through the old order prepared the way for the new life that the Christian gospel has now made possible. It is a life that people of all nations can have through faith and obedience (25-27).
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Flemming, Donald C. "Commentary on Romans 16". "Brideway Bible Commentary". https://www.studylight.org/
Second Sunday after Easter